VIRUS

Advanced Methods of Adenovirus Vector Production for Human Gene Therapy: Roller Bottles, Microcarriers, and Hollow Fibers

The production of adenoviral vectors for research purposes using conventional methods such as T flasks or roller bottles consumes significant amounts of time and space. When 293 cells are adapted to suspension culture large quantities of adenoviral vectors can be produced in a single FiberCell® Systems cartridge. High cell density makes for rapid and uniform infection kinetics within the ECS of the FiberCell® Systems cartridge.
  • Can produce 1-3x1013 virus particles, equal to 20 roller bottle
  • Closed, biosafe system
  • Utilizes serum free medium
  • Precise control of pH for optimum infections

Cick here to enlarge chart


Cick here to enlarge chart

SUGGESTED ORDERING FOR VIRUS CULTURE:

BIOREACTOR
P3202
The FiberCell® Systems Duet more info
CARTRIDGES
Catalog No.
Size
Surface Area
Fiber Type
Packing Density
ECS Vol
MWCO 50%
Max. Cell#
  
C2011
Medium
3000 cm2
high flux PS
50%
15 ml
20kd
109
more info
C2018
Large
1.2 m2
high flux PS
50%
70 ml
20kd
5 x 1010
 more info
RESERVOIR CAPS
A1005
33 mm Reservoir Cap more info
A1006
38 mm Reservoir Cap more info


 

A single FiberCell hollow fiber cartridge is equivalent to harvesting 20 roller bottles daily.
A single FiberCell Systems hollow fiber cartridge is equivalent to harvesting 20 roller bottles daily.