Malaria
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Traditional plasmodium culture protocols involve numerous flasks, tedious manipulations and time consuming medium changes. Culture of plasmodium in hollow fiber offers a simple method for the support of red blood cells at up to 100% hematocrit and parasitemia levels of 14 - 18%. A single C2011 FiberCell™ cartridge is equivalent to up to 65 T25 flasks.
Data courtesy of Dr. Joshua Zimmerberg, Dr, Svetlana Glushakova and Dr. Tao Li, NIH. |
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Hematocrit in FiberCell™ Bioreactor
*Control Flask (T25) contains 5-mL cell suspension with 6% parasitemia at 6% hematocrit on day 4 in culture.
A single FiberCell™ cartridge can replace 60 flasks.
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